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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Addict Biol. 2017 Jan 11;23(1):130–141. doi: 10.1111/adb.12488

Figure 1.

Figure 1

Experimental timeline and schematic overview of distress tolerance task. A) Experimental timeline. TR = Initial Training; TT = Titration Task, DT = Distress Tolerance Task, SA = Cocaine Self-Administration, EX = Cocaine Extinction. See main text for details of task design. B) Schematic of a single distress tolerance trial. Responses during the cue period (Cue ON) were rewarded with a single sucrose pellet. Responses during the Precue or Postcue periods were considered ‘errors’ and were signaled by a noise and a 5 s timeout. The duration of the cue ON period titrated according to task performance in the Titration task, and progressively decreased in the Distress Tolerance task.