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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Addict Biol. 2017 Jan 11;23(1):130–141. doi: 10.1111/adb.12488

Figure 5.

Figure 5

Relationship between distress tolerance following abstinence and subsequent drug seeking behavior during extinction. A) Experimental timeline highlighting analysis time points. B) Rats exhibit ‘incubation of craving’ (i.e., increased drug seeking) following 30 days of drug abstinence, C) Distress tolerance after abstinence had a trend to predict number of responses under extinction. D) There was a significant interaction between distress tolerance and impulsivity: In animals with low impulsivity, low distress tolerance significantly predicted more responses under extinction. No such relationship was seen in animals with high impulsivity.