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. Author manuscript; available in PMC: 2017 Sep 30.
Published in final edited form as: Biometrics. 2017 Jan 11;73(3):949–959. doi: 10.1111/biom.12646

Table 1.

Mean, Median, and Standard Deviation (SD) of the square root of the average squared errors (RASEs) defined in (22) for the estimated varying coefficients θ̂D(w), θ̂S(w) and θ̂A(w) in 1000 simulation replicates by using the proposed parameter cascading method (PC) and the two-stage method (TS). Here a is the standard deviation of ε in (2), θD(·) is the diffusion rate, θS(·) is the drift rate, θA(·) is the reaction rate.

σ = 0.05 σ = 0.02
PC TS PC TS
RMSE of θ̂D(w) Mean ×102 1.54 22.76 1.29 15.85
Median ×102 1.53 22.55 1.28 15.88
SD ×103 3.53 40.22 1.58 21.29

RMSE of θ̂S(w) Mean ×103 1.86 14.94 1.09 10.03
Median ×103 1.85 14.50 1.10 9.90
SD ×104 6.08 43.58 2.78 21.09

RMSE of θ̂A(w) Mean ×103 1.88 3.46 1.87 2.22
Median ×103 1.88 3.38 1.87 2.19
SD ×104 0.30 7.19 0.11 1.85