Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jul 11;7:5067. doi: 10.1038/s41598-017-05314-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Effects of Inh2-B1 enhances the bactericidal activity of Ceftriaxone and Cefotaxime. Time-to-kill experiment shows Optical Density (OD) at 620 nm and viable bacterial counts (colony forming units) of (A,B) MW2-WT at different time intervals, when grown in the presence and absence of Inh2-B1 inhibitor. Optical Density and corresponding Colony forming units of (C,D) MW2-WT and (E,F) MW2ΔSTK1 cultures in the presence or absence 50 µM Inh2-B1, 1.51 µM (1 µg/ml) Ceftriaxone, 2.125 µM (1 µg/ml) Cefotaxime, and combination of Inh2-B1 plus Ceftriaxone, and Inh2-B1 plus Cefotaxime. The experiments were carried out as described in the Materials and Method section using Muller-Hinton broth and seeded with 4 × 10⁶ CFUs of S. aureus MW2-Wild type or MW2ΔSTK1 strains per well. Each data points represent Mean ± S.D. P values of significance (**<0.01, ***<0.001) were determined using the t-test with Welch’s corrections. NS-Not significant.