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. 2017 Jul 11;7:5088. doi: 10.1038/s41598-017-03915-2

Table 1.

Signals within HLA associated with IgA susceptibility at the GWAS significance level-P < 5E-08-after imputation of GWAS data.

SNP Position in chr 6 (GRCh37) Reference allele P OR [CI 95%]
rs9275260 32.661.575 C 3.42E-09 0.56 [0.46–0.68]
rs9275259 32.661.572 C 3.42E-09 0.56 [0.46–0.68]
rs9275284 32.663.073 C 4.30E-09 0.56 [0.46–0.68]
rs9275285 32.663.080 A 4.30E-09 0.56 [0.46–0.68]
rs9275286 32.663.143 T 4.30E-09 0.56 [0.46–0.68]
rs9275288 32.663.203 A 4.30E-09 0.56 [0.46–0.68]
rs9275292 32.663.289 C 4.30E-09 0.56 [0.46–0.68]
rs9275244 32.660.881 G 4.92E-09 0.56 [0.46–0.68]
rs5000633 32.663.610 C 5.20E-09 0.56 [0.46–0.68]
rs2395522 32.664.722 A 5.25E-09 0.56 [0.46–0.68]
rs9275279 32.662.843 G 5.32E-09 0.56 [0.46–0.68]
rs9275281 32.662.920 G 5.32E-09 0.56 [0.46–0.68]
rs4248168 32.659.743 G 5.46E-09 0.56 [0.47–0.68]
rs9275224 32.659.878 A 5.46E-09 0.56 [0.47–0.68]
rs4713580 32.659.994 C 5.46E-09 0.56 [0.47–0.68]
rs4713584 32.660.237 C 5.46E-09 0.56 [0.47–0.68]
rs9275225 32.660.262 G 5.46E-09 0.56 [0.47–0.68]
rs5002704 32.659.279 T 5.67E-09 0.56 [0.46–0.68]
rs4713581 32.660.023 T 6.08E-09 0.56 [0.47–0.68]
rs4713583 32.660.153 T 6.08E-09 0.56 [0.47–0.68]
rs9275228 32.660.347 G 6.12E-09 0.56 [0.47–0.68]
rs9275227 32.660.337 C 6.12E-09 0.56 [0.47–0.68]
rs9275295 32.663.391 A 6.19E-09 0.56 [0.46–0.68]
rs9275277 32.662.677 G 7.33E-09 0.57 [0.47–0.69]
rs9275276 32.662.676 T 7.33E-09 0.57 [0.47–0.69]
rs9275245 32.660.943 A 7.89E-09 0.57 [0.47–0.69]
rs5002708 32.659.357 T 8.00E-09 0.57 [0.47–0.69]
rs5002707 32.659.337 T 8.00E-09 0.57 [0.47–0.69]
rs67838634 32.662.128 G 8.89E-09 1.76 [1.45–2.13]
rs9275222 32.659.516 T 1.28E-08 1.75 [1.44–2.12]
rs6457617 32.663.851 C 1.44E-08 0.57 [0.47–0.70]
rs6457620 32.663.999 G 1.44E-08 0.57 [0.47–0.70]
rs5002702 32.659.158 G 1.47E-08 0.57 [0.47–0.70]
rs9275226 32.660.311 C 1.49E-08 0.57 [0.47–0.70]
rs9275230 32.660.442 A 1.49E-08 0.57 [0.47–0.70]
rs5002705 32.659.319 C 1.60E-08 0.57 [0.47–0.70]
rs4713582 32.660.051 T 1.63E-08 0.57 [0.47–0.70]
rs4711304 32.660.170 T 1.65E-08 0.58 [0.47–0.70]
rs9275246 32.661.003 C 2.11E-08 0.58 [0.48–0.70]
rs4713587 32.659.535 G 2.36E-08 0.58 [0.48–0.70]
rs9275247 32.661.015 T 2.87E-08 0.58 [0.48–0.70]
rs9275231 32.660.505 C 2.81E-08 1.73 [1.42–2.09]

HLA: Human leukocyte antigen; IgA: Immunoglobulin-A; GWAS: genome-wide association study; SNP: single nucleotide polymorphism; chr: chromosome; OR: odds ratio; CI: confidence interval.