Table 3.
Gene expression in M. tuberculosis treated by IMB-YH-8 with microarray and RT-PCR.
| Systematic name | Gene | Description | Regulation | Fold induction in microarray (mean ± SD) | Real-time reverse transcription PCR | |
|---|---|---|---|---|---|---|
| Normalized ΔCt (mean ± SD) | Mean fold change (2ΔΔCt Value) | |||||
| Rv3914 | trxC | thioredoxin TrxC | Up | 8.03 ± 0.33 | 2.455 ± 0.06 | 5.48 |
| Rv3913 | trxB2 | thioredoxin reductase | Up | 6.90 ± 0.75 | 2.940 ± 0.07 | 7.67 |
| Rv2466c | hypothetical protein Rv2466c | Up | 6.86 ± 1.93 | 6.325 ± 2.51 | 80.17 | |
| Rv3221A | rshA | anti-sigma factor RshA | Up | 6.07 ± 0.33 | 8.045 ± 0.59 | 264.11 |
| Rv3223c | sigH | ECF RNA polymerase sigma factor SigH | Up | 2.92 ± 0.09 | 2.555 ± 0.11 | 5.88 |