Table 2.
Single locus analysis for all the single nucleotide polymorphisms (SNPs) genotyped
| SNP | Model | Maternal | Fetal | ||||
|---|---|---|---|---|---|---|---|
| OR | P | P* | OR | P | P * | ||
| ACE I/D | dominant | 1.04 (0.73–1.48) | 0.822 | 0.997 | 0.84 (0.60–1.19) | 0.327 | 0.997 |
| recessive | 0.89 (0.60-1.33) | 0.578 | 0.997 | 0.87 (0.56–1.33) | 0.516 | 0.997 | |
| ACE G2350A | dominant | 1.11 (0.79–1.55) | 0.368 | 0.997 | 0.88 (0.63–1.22) | 0.442 | 0.997 |
| recessive | 0.86 (0.52–1.43) | 0.559 | 0.997 | 0.72 (0.40–1.30) | 0.274 | 0.997 | |
| AGT M235T | dominant | 1.10 (0.79–1.53) | 0.651 | 0.997 | 1.40 (1.01–1.94) | 0.043 | 0.930 |
| recessive | 0.82 (0.45–1.51) | 0.455 | 0.997 | 0.98 (0.53–1.80) | 0.946 | 1.000 | |
| AGT T174M | dominant | 1.00 (0.66–1.50) | 0.781 | 0.997 | 0.79 (0.51–1.23) | 0.500 | 0.997 |
| recessive | 1.85 (0.49–6.96) | 0.355 | 0.997 | 5.95 (0.66–53.56) | 0.178 | 0.997 | |
| AT1R A1166C | dominant | - | 0.505 | 0.997 | - | 0.600 | 0.997 |
| recessive | 1.05 (0.63–1.74) | 1.000* | 1.000 | 0.95 (0.54–1.67) | 1.000* | 1.000 | |
Statistical significance was tested at P < 0.05; OR, odds ratio; CI, confidence interval; *, using Fisher exact probability; “-” means the result could not be calculated because of limited counts; P *, corrected P-value after FDR procedure.