Table 4.
Genetic association of the maternal and fetal genotypes (SNPs in ACE, AGT, and AT1R) with PE.
| SNP | Genotype | Maternal genotype | Offspring genotype | ||
|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | ||
| ACE I/D | DD | reference | 0.491 | reference | 0.039 |
| ID | 1.12 (0.79–1.59) | 0.80 (0.64–1.22) | |||
| II | 1.31 (0.83–2.04) | 0.58 (0.36–0.91) | |||
| ACE G2350A | AA | reference | 0.589 | reference | 0.045 |
| AG | 0.99 (0.67–1.46) | 0.86 (0.61–1.21) | |||
| GG | 1.19 (0.63–2.26) | 0.47 (0.26–0.88) | |||
| AGT M235T | TT | reference | 0.570 | reference | 0.010 |
| MT | 0.97 (0.70–1.34) | 1.24 (0.70–2.23) | |||
| MM | 0.70 (0.39–1.27) | 1.54 (1.13–2.10) | |||
| AGT T174M | TT | reference | 0.085 | Reference | 0.442 |
| MT | 1.68 (0.99–2.82) | 0.76 (0.46–1.26) | |||
| MM | 3.16 (0.60–16.78) | 1.35 (0.33–5.55) | |||
| AT1R A1166C | AA | reference | 0.699 | Reference | 0.364 |
| AC | 1.17 (0.73–1.89) | 0.69 (0.41–1.15) | |||
| CC | 2.05 (0.17–24.31) | - |
“-” means the result could not be calculated because of limited counts.