Table 5.

Genetic association of the maternal and fetal genotypes (SNPs in ACE, AGT, and AT1R) with mild (m)PE and severe (s)PE.

SNP	Genotype		Maternal genotype		Offspring genotype
			OR (95% CI)	P	OR (95% CI)	P
ACE I/D	DD		reference		reference
	ID	m	1.08 (0.64–1.89)	0.491	0.43 (0.18–1.03)	0.100
	II		1.91 (0.32–11.44)		0.27 (0.06–1.17)
	ID	s	1.07 (0.66–1.74)	0.654	1.14 (0.76–1.71)	0.054
	II		1.31 (0.71–2.43)		0.65 (0.36–1.16)
ACE G2350A	AA		reference		reference
	AG	m	0.96 (0.45–2.07)	0.260	0.52 (0.23–1.15)	0.215
	GG		2.44 (0.75-8.01)		0.39 (0.09–1.68)
	AG	s	0.95 (0.81–1.63)	0.700	0.91 (0.65–1.27)	0.354
	GG		1.16 (0.65–2.05)		0.64 (0.36–1.17)
AGT M235T	TT		reference		reference
	MT	m	0.74 (0.31–1.77)	0.508	1.32 (0.31–1.74)	0.477
	MM		0.45 (0.39–5.44)		1.47 (0.39–5.52)
	MT	s	0.94 (0.67–1.33)	0.437	1.19 (0.62–2.30)	0.004
	MM		0.66 (0.35–1.32)		1.74 (1.25–2.41)
AGT T174M	TT		reference		reference
	MT	m	2.00 (0.18–22.04)	0.085	1.50 (0.42–5.31)	0.442
	MM		2.33 (0.60–9.02)		-
	MT	s	1.60 (0.90–2.84)	0.174	0.67 (0.39–1.16)	0.283
	MM		4.31 (0.43–43.69)		1.22 (0.29–5.11)
AT1R A1166C	AA		reference		reference
	AC	m	1.17 (0.21–2.83)	0.928	0.76 (0.21–2.80)	0.921
	CC		-		-
	AC	s	1.26 (0.76–2.07)	0.545	0.67 (0.38–1.16)	0.361
	CC		2.46 (0.21–29.49)		-

“-” means the result could not be calculated because of limited counts.