Table 2. Demographic and laboratory characteristics of patients according to survival status within 90 days of discharge following hospitalization for AECOPD.
Characteristics | Died within 90 days months post discharge (N=16) | Alive at 90 months post discharge (N=165) | P value |
---|---|---|---|
Demographics | |||
Age | 78±9 | 70±10 | 0.004 |
Sex (male/female) | 12/4 | 81/84 | 0.066 |
BMI (kg/m2) | 23±5 | 26±7 | 0.090 |
FEV1 (% predicted) | 41±19 | 44±18 | 0.349 |
BMI (kg/m2), mean (±SD) | 23.3±5.8 | 26.1±6.8 | 0.090 |
Comorbidity, n (%) | |||
Coronary artery disease | 5 (31%) | 40 (24%) | 0.550 |
Congestive heart failure | 4 (25%) | 25 (15%) | 0.294 |
Depression | 3 (19%) | 33 (20%) | 1.00 |
Arrhythmia | 4 (25%) | 26 (16%) | 0.309 |
Chronic kidney disease | 5 (31%) | 11 (7%) | 0.069 |
Osteoporosis | 4 (25%) | 26 (16%) | 0.309 |
Total number of comorbidities, mean (± SD) | 5.1±1.8 | 4.6±2.7 | 0.15 |
Index hospital admission | |||
Antimicrobial therapy | 13 | 135 | 1.00 |
Systemic corticosteroid therapy | 13 | 138 | 1.00 |
Bronchodilator therapy | 16 | 165 | 1.00 |
Length of stay (days)* | 5.5 [2.3–11] | 3 [1–6] | 0.313 |
Biomarkers | |||
Haemoglobin (g/dL) | 118±15 | 137±20 | 0.000 |
Neutrophil | 13±11 | 8±4 | 0.023 |
NLR | 13±10 | 7±8 | 0.004 |
PLR | 348±228 | 208±164 | 0.010 |
Urea | 11±7 | 7±7 | 0.015 |
Data is presented as mean ± standard deviation for normally distributed data. *, median (range) for non-Gaussian distributed data. AECOPD, acute exacerbation of COPD; CI, confidence interval; OR, odds ratio; BMI, body mass index; FEV1, forced expiratory volume in 1 second; SD, standard deviation; NLR, neutrophil lymphocyte ratio; PLR, platelet-to-lymphocyte ratio.