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. 2017 Jul 12;8:750. doi: 10.3389/fimmu.2017.00750

Table 1.

Superiority of the F1 over the NH36 antigen in interferon (IFN)-γ and tumor necrosis factor alpha (TNF-α)/interleukin (IL)-10 ratios.

Antigens
F1
NH36
Patients Endemic controls (EC) Asym.a Cured cutaneous leishmaniasis (CCL) CVL EC Asym. CCL CVL
IFN-γ (pg/ml) 58 147 195 231 37 126 156 135
TNF-α (pg/ml) 451 448 357 906 232 254 285 516
IL-10 (pg/ml) 117 109 114 141 94 102 101 140
IFN-γ/IL-10 ratio 0.5 1.3 1.7 1.6 0.4 1.2 1.6 1
TNF-α/IL-10 ratio 3.9 4.1 3.1 6.4 2.4 2.5 2.8 3.7
IFN-γ/IL-10 ratio % enrichment 20 8 6 38
TNF-α/IL-10 ratio % enrichment 38 39 10 42

Calculation was performed according to the following equation = (F1-NH36/F1) values × 100 = protective increment. doi: 10.1371/journal.pntd.0000866.t003.

aAsymptomatic.