Figure 3.

Hazard ratios for primary and secondary endpoints. A primary composite cardiovascular events consisted of the following groups: sudden death; fatal or non-fatal stroke; fatal or non-fatal myocardial infarction; hospitalization due to unstable angina; new onset of heart failure (New York Heart Association class II–IV); new onset or worsening of peripheral arterial disease; and renal events (defined as serum creatinine level doubled to over 2 mg dl⁻¹, serum creatinine ⩾4.0 mg dl⁻¹ or renal dialysis). Hard composite cardiovascular events consist of cardiovascular death, fatal or non-fatal myocardial infarction and stroke excluding TIA. ARB, angiotensin receptor blocker; BB, β-blocker; CI, confidence interval; CV, cardiovascular; TD, thiazide diuretic; TIA, transient ischemic attack.