Figure 4.

Kaplan–Meier curves for time to first primary and secondary endpoint. Primary composite cardiovascular events: sudden death, fatal or non-fatal stroke, fatal or non-fatal myocardial infarction, hospitalization due to unstable angina, new onset of heart failure (New York Heart Association class II–IV), new onset or worsening of peripheral arterial disease, and renal events (defined as serum creatinine level doubled to over 2 mg dl⁻¹, serum creatinine ⩾4.0 mg dl⁻¹, or renal dialysis). Hard composite cardiovascular events; cardiovascular death, non-fatal myocardial infarction and non-fatal stroke excluding transient ischemic attack. ARB, angiotensin receptor blocker; BB, β-blocker; CV, cardiovascular; TD, thiazide diuretic; TIA, transient ischemic attack.