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. 2016 Jul 14;39(12):868–873. doi: 10.1038/hr.2016.88

Table 1. Baseline characteristics of the study population by ULLA total severity score.

  Total severity score
 
  I II III IV V VI P-value
N 36 86 89 27 63 19  
Age, mean (s.d.) 59 (10) 69 (10) 69 (9) 72 (7) 74 (8) 74 (8) <0.001
               
Gender             <0.001
 F 29 (81%) 62 (72%) 49 (55%) 9 (33%) 22 (35%) 3 (16%)  
 M 7 (19%) 24 (28%) 40 (45%) 18 (67%) 41 (65%) 16 (84%)  
Altered ABI 2 (6%) 7 (8%) 10 (11%) 7 (26%) 34 (54%) 19 (100%) <0.001
BMI, mean (s.d.) 27.2 (5.1) 27.3 (3.9) 27.7 (4.9) 28.9 (4.9) 26.1 (3.5) 25.8 (2.9) 0.043
Packs per year, median (IQR) 3 (0, 11) 0 (0, 8) 15 (0, 30) 11 (0, 36) 23 (0, 38) 45 (18, 60) <0.001
               
Smoking status             <0.001
 Never 13 (36%) 55 (64%) 32 (36%) 9 (33%) 16 (25%) 2 (11%)  
 Former 14 (39%) 21 (24%) 40 (45%) 14 (52%) 35 (56%) 12 (63%)  
 Active 9 (25%) 10 (12%) 17 (19%) 4 (15%) 12 (19%) 5 (26%)  
Hypertension 15 (42%) 53 (62%) 65 (73%) 19 (70%) 55 (87%) 15 (79%) <0.001
Diabetes 3 (8%) 24 (28%) 26 (29%) 15 (56%) 31 (49%) 6 (32%) <0.001
Dyslipidemia 17 (47%) 49 (57%) 60 (67%) 16 (59%) 39 (62%) 12 (63%) 0.42
CV family history 28 (78%) 67 (78%) 75 (84%) 16 (59%) 50 (79%) 16 (84%) 0.15
Sedentary lifestyle 5 (14%) 18 (21%) 27 (30%) 5 (19%) 26 (41%) 5 (26%) 0.025
CV events 3 (8%) 12 (14%) 19 (21%) 8 (30%) 24 (38%) 10 (53%) <0.001

Abbreviations: ABI, ankle–brachial index; BMI, body mass index; CV, cardiovascular; ULLA, ultrasonographic lower limbs atherosclerosis.