Table 1.

Clinicopathologic characteristics of 102 patients.

Variable	Category	Metformin group	Nonmetformin group	P
Age		63.57, mean	63.74, mean	0.596
Gender	Female	10	25	0.855
	Male	18	49
Drinking history	Yes	8	12	0.161
	No	20	62
Smoking history	Yes	7	23	0.547
	No	21	51
Family history	Yes	5	2	0.016∗
	No	23	72
BMI		25.46, mean	24.73, mean	0.889
CEA		5.68, mean	4.11, mean	0.228
CA19-9		9.7, mean	11.97, mean	0.172
Sulfonylurea	Yes	13	34	0.965
	No	15	40
Insulin	Yes	4	30	0.018∗
	No	24	44
Site	Right	7	12	0.787
	Transverse	1	4
	Left	1	5
	Sigmoid	6	13
	Rectum	13	40
Histologic grade	I-II	22	63	0.427
	III	6	11
T	T1–3	18	34	0.098
	T4	10	40
N	N0	21	39	0.041∗
	N1-2	7	35
E-cadherin	Positive	19	30	0.014∗
	Negative	9	44
Vimentin	Positive	8	42	0.011∗
	Negative	20	32

^∗ P < 0.05.