Table 4.

Multivariable model for the outcome of late PH in all infants and in infants with multiple studies

Variable	Odds ratio	95% CI	p-value
Overall multivariable model for the outcome of late PH
Gestational age	0.9	0.8–1.1	0.22
Atrial septal defect (ASD vs. None)	2.9	1.4–6.1	<0.01*
Growth restriction	2.7	1.2–6.3	0.02*
Caffeine	0.4	0.2–0.8	0.01*
Positive-pressure ventilation	1.5	0.8–2.9	0.16
Multivariable model for the outcome of late PH, among infants with multiple studies
Gestational age	0.9	0.7–1.1	0.18
Atrial septal defect (ASD vs. None)	5.9	2.0–16.5	<0.001*
Growth restriction	3.7	1.3–10.7	0.01*
Caffeine	0.8	0.3–1.8	0.53
Positive-pressure ventilation	1.4	0.6–3.3	0.38

A) The association between significant co-variates and the outcome of late pulmonary hypertension was evaluated. B) The association between significant co-variates and the outcome of late pulmonary hypertension in infants with multiple studies was evaluated. Gestational age and positive-pressure ventilation were forced into the model. Multivariable logistic regression was used to derive odds ratios and 95% confidence intervals. *p ≤ 0.05 was significant