Table II.
Price calculation of adjuvant trastuzumab (18 cycles) per weight categories
| Weight (kilogram) | 87,5 | 84 | 75 | 62,5 | 56,25 | 50 |
| IV loading dose vials | 5 | 4,5 | 4 | 3,5 | 3 | 3 |
| IV subsequent dose | 3,5 | 3,5 | 3 | 2,5 | 2,5 | 2 |
| Total vials | 64,5 | 64 | 55 | 46 | 45,5 | 37 |
| Price IV (€) | 33400,04 | 33141,12 | 28480,65 | 23820,18 | 23561,27 | 19157,71 |
| Price SC (€) | 28480,50 | 28480,50 | 28480,50 | 28480,50 | 28480,50 | 28480,50 |
| Difference IV – SC (€) | + 4919,54 | + 4660,62 | + 0,15 | - 4660,32 | - 4919,24 | - 9320,79 |
½ vial = >0,0 and < 0,5 or >0,5 and < 1,0; Loading dose IV in number of vials (weight (kg) x 8mg)/150; Subsequent dose IV in number of vials (weight (kg) x 6 mg)/150; Total vials (18 cycles) = Loading number of vials + 17 x Subsequent number of vials; 1 IV vial is 517,83€; 1 SC vial is 1582,25€.