Table 2. Cacna1c mRNA Expression in Alcohol-Dependent and Nondependent Rats after 0, 1, 3, 7, and 21 Days of Abstinence.
Region | Days of abstinence | Non-dep. (nCi/g) | Alc. dep. (nCi/g) | N Non-dep. | N Alc. dep. |
---|---|---|---|---|---|
CA1 | 0 | 11.28±1.2 | 13.75±1.0 | 8 | 6 |
1 | 13.69±0.7 | 10.38±0.9 | 8 | 8 | |
3 | 10.66±0.5 | 11.04±1.0 | 6 | 7 | |
7 | 10.63±0.6 | 13.05±1.5 | 8 | 8 | |
21 | 7.54±0.1 | 13.33±1.0 | 7 | 8 | |
CeA | 0 | 15.62±0.7 | 21.45±0.5 | 8 | 6 |
1 | 18.17±0.9 | 13.70±0.4 | 7 | 8 | |
3 | 18.70±0.6 | 16.78±0.7 | 6 | 8 | |
7 | 13.57±0.6 | 16.71±1.4 | 8 | 7 | |
21 | 12.44±0.4 | 15.99±0.6 | 7 | 8 | |
BLA | 0 | 13.33±0.66 | 17.65±0.3 | 8 | 6 |
1 | 15.47±0.6 | 12.88±0.3 | 8 | 8 | |
3 | 15.76±0.6 | 15.47±0.8 | 6 | 8 | |
7 | 15.12±0.5 | 16.73±1.6 | 8 | 7 | |
21 | 11.86±0.4 | 13.76±0.6 | 7 | 8 |
Abbreviations: Alc. dep., alcohol dependent; Non-dep., nondependent; BLA, basolateral amygdala; CA1, dorsal hippocampal cornus ammon (CA) region; CeA, central amygdala.
Data were measured in nCi/g, shown as mean±SEM. For details on treatment, see Materials and Methods.