Figure 6.

Progress of ⁶⁸Ga activity during one automated synthesis run for the routine pharmaceutical production of ⁶⁸Ga-DOTATOC—synthesis time: 14 min, time until application: 20 min (vertical black line), start activity: 1.85 GBq, activity after synthesis: 1.20 GBq, applicable activity for patients: 1.13 GBq (horizontal black line). Blue line: progress of eluted activity of ⁶⁸Ga that is used for the automated synthesis run. Red line: regeneration of ⁶⁸Ga activity in the ⁶⁸Ge/⁶⁸Ga generator after elution. The loss of activity at the end of the synthesis results from the loss of final product due to adsorption processes during the sterile filtration and in the synthesis module and also because of the taken samples for the quality control.