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. 2017 Mar 27;12(9):753–765. doi: 10.2217/fmb-2017-0022

Figure 5. . Mutation RpoB H526D impairs Mycobacterium tuberculosis growth in mouse lungs.

Figure 5. 

BALB/c mice were aerosol infected with equal inocula of the RpoB H526D mutant, wild-type or complemented strains. (A) Log 10 CFU/lung (*p = 0.02; **p = 0.006; ***p < 0.0001); (B) Bodyweights of Mycobacterium tuberculosis (Mtb)-infected mice. (C) Lung weights of Mtb-infected mice (*p = 0.05). (D) Spleen weights of Mtb-infected mice (*p = 0.03; **p = 0.02; ***p = 0.0002).

comp: Complemented strain of the RpoB H526D mutant.