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. 2017 Mar 27;12(9):753–765. doi: 10.2217/fmb-2017-0022

Table 1. . In vitro competitive assays reveal fitness cost of the RpoB H526D mutant.

Strain mixture 7H9 broth (CFU/ml)
Progressive hypoxia (CFU/ml)
  Day 0 Stationary phase (day 10) Day 0 7 days after color change (day 21)
CDC1551
1.2 × 106
2.5 × 108
7 × 104
1.3 × 105
rpoB mutant
2.2 × 106
9.4 × 107
1.5 × 105
6.5 × 104
Ratio   0.70   -2.4