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. 2017 Jul 10;3(7):e00354. doi: 10.1016/j.heliyon.2017.e00354

Table 2.

In vitro inhibitory activity of alectinib metabolites against ALK or tumour cell growth.

Metabolite IC50 (nmol/L)
ALK Cell growth
Alectinib* 1.9 33
M1b 1.6 320
M4 1.2 37

Values represent the geometric mean of triplicates.

*

This value is referred [7].