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Plasma protein binding of alectinib and M4.
| Concentration |
Protein Binding |
|
|---|---|---|
| (μg/mL) | (%) | |
| Alectinib | 0.1 | 99.6 ± 0.1 |
| 1 | 99.7 ± 0.0 | |
| 10 | 99.7 ± 0.0 | |
| M4 | 0.3 | 99.1 ± 0.1 |
| 1 | 99.5 ± 0.0 | |
| 2 | 99.5 ± 0.1 |
Values represent the mean ± standard deviation of triplicates.
