FIGURE 3.

Co-occurrence network between taxa and biomarkers. Th: T-helper; IPF: idiopathic pulmonary fibrosis. compPLS was utilised to evaluate associations between the lung microbiome and local/systemic biomarkers, which were categorised as Th1, Th2, Th17 and/or IPF immunological phenotype. a) Associations between taxa and bronchoalveolar lavage (BAL) fluid cytokines. b) Associations between taxa and BAL cell supernatant cytokines. c) Associations between taxa and plasma cytokines. Negative associations are in red and positive associations are in grey; edge weight is scaled to represent the degree of confidence for the associations.