TABLE 1.
Subjects | 10 |
Age years | 69.0 (63.7–76.0) |
Male | 8 (80) |
Smoking status | |
Current | 0 |
Ex | 5 (50) |
Never | 5 (50) |
Pack-years (smokers) | 20 (10–30) |
Clinical | |
Biopsy done | 4 (40) |
PASP elevated | 6 (60) |
PAP mmHg | 36.8 (33.2–40.7) |
N-acetyl cysteine treatment | 4 (40) |
Pulmonary function | |
FVC % pred | 73.5 (68.2–84.2) |
TLC % pred | 71.0 (60.0–77.0) |
DLCO % pred | 47.5 (39.5–56.5) |
6MWT m | 420 (287–490) |
BAL | |
BAL cells obtained ×106 | 19.2 (13.8–31.9) |
Macrophages % | 78.0 (69.0–91.2) |
Lymphocytes % | 5.0 (3.0–9.3) |
Neutrophils % | 9.0 (3.5–24.3) |
Eosinophils % | 0.75 (0–2.25) |
Data are presented as n, median (interquartile range) or n (%). PASP: pulmonary artery systolic pressure; PAP: pulmonary arterial pressure; FVC: forced vital capacity; TLC: total lung capacity; DLCO: diffusing capacity of the lung for carbon monoxide; 6MWT: 6-min walk test.