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. 2017 Jul 10;12(7):e0180878. doi: 10.1371/journal.pone.0180878

Table 2. Regression coefficients, ORs, and 95% CIs of the final combined model* for predicting SPTD at <32 weeks of gestation.

Predictor Beta-coefficient SE OR (95% CI) P-value
Cervical dilatation (cm) 0.943 0.262 2.56 (1.53–4.29) <0.001
Cervicovaginal fluid VDBP (μg/mL) 0.875 0.382 2.39 (1.13–5.07) 0.022
Use of corticosteroid 1.866 0.817 6.46 (1.30–32.03) 0.022
Constant -3.552 0.937 0.029 <0.001

OR, odds ratio; CI, confidence interval; SPTD, spontaneous preterm delivery; SE, standard error; VDBP, vitamin D binding protein; TIMP, tissue inhibitor of metalloproteinases; DKK, Dickkopf; CVF, cervicovaginal fluid; CRP, C-reactive protein. The formula that was generated to predict SPTD at <32 weeks was as follows: Y = logₑ (Z) = -3.552 + 0.943 × [cervical dilatation (in cm)] + 0.875 × [cervicovaginal fluid VDBP (in μg/mL)] + 1.866 × (1 for use of corticosteroid, 0 for non-use of corticosteroid). Z = eY and risk (%) = [(Z / (1+Z)] × 100.

*Final model resulting from a forward regression analysis including the following predictive parameters: VDBP, TIMP-1, and DKK3 in the CVF, serum CRP, cervical dilatation, vaginal progesterone therapy, and use of corticosteroids.