Table 2.
Associations between the composite fetal imprinted gene allele score and the prevalence of GDM.
Cohorts | Statistical model | Odds ratio per allele | P-value | Pseudo r2 (%) | Number of observations |
---|---|---|---|---|---|
Cambridge Baby Growth Study & Cambridge Wellbeing Study combined | Unadjusted | 1.44 (1.15, 1.80) | 1.3 × 10–3 | 1.7 | 988 |
Cambridge Baby Growth Study & Cambridge Wellbeing Study combined | Adjusted for maternal age | 1.42 (1.14, 1.78) | 1.9 × 10–3 | 1.6 | 956 |
Cambridge Baby Growth Study & Cambridge Wellbeing Study combined | Adjusted for pre-pregnancy maternal BMI |
1.38 (1.02, 1.86) | 0.035 | 4.4 | 556 |
Cambridge Baby Growth Study & Cambridge Wellbeing Study combined | Adjusted for maternal age and pre-pregnancy maternal BMI |
1.37 (1.01, 1.84) | 0.041 | 4.4 | 534 |
Cambridge Baby Growth Study | Unadjusted | 1.42 (1.09, 1.86) | 0.011 | 1.5 | 671 |
Cambridge Wellbeing Study | Unadjusted | 1.50 (1.00, 2.24) | 0.049 | 2.2 | 317 |
Odds ratios are mean (95% confidence interval).