Table 1. Effects of the subcutaneous administration of 5 mg/kg of DPDPE alone or combined with 2 mg/kg of naltrindole on the mechanical allodynia (von Frey filaments strength, g) in db/db mice.

Treatment	Mechanical response von Frey filaments strength (g)
saline-vehicle	1.7 ± 0.1
DPDPE -vehicle	3.0 ± 0.1*
DPDPE-naltrindole	1.7 ± 0.1
saline-naltrindole	1.8 ± 0.1

Results are shown as mean values ± SEM; n = 6 animals per experimental group.

* p < 0.05 denotes significant differences versus saline plus vehicle treated group (one way ANOVA, followed by the Student Newman Keuls test)