. 2017 Jul 10;12(7):e0180964. doi: 10.1371/journal.pone.0180964

Table 2. Renal structural characteristics of the 243 participants in RASS with type 1 diabetes who had plasma bradykinin and related peptides measured at baseline.

Variable	Baseline	5 Years	P-value
GBM width (nm)	477±95	487±97	0.061
Vv(Mes/glom) (%)	19±4	21±5	<0.001
Vv(Int/cortex) (%)^*	11±4	17±5	<0.001
Sv(PGBM/glom) (μm²/μm³)	13±2	11±2	<0.001
GlomV (x10⁶μm³)^†	1.7±0.5	-	-
TFS/glom (x10⁵ μm²)^†	2.2±0.7	-	-

* N = 189

^† N = 156

Data are means±SD. P-values are for changes in morphometric measurements over 5 years. Abbreviations used: GBM, glomerular basement membrane; Sv(PGBM/glom), surface density of the peripheral glomerular basement membrane; Vv(Int/cortex), interstitial cortical fractional volume; Vv(Mes/glom), mesangial fractional volume per glomerulus; GlomV, mean glomerular volume; TFS/glom, total filtration surface per glomerulus.