Skip to main content
. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Biochim Biophys Acta. 2017 Mar 18;1864(7):1183–1194. doi: 10.1016/j.bbamcr.2017.03.007

Figure 2. Vesicle trafficking mechanisms that regulate the integrity and disruption of the intestinal epithelial barrier.

Figure 2

The diagram depicts a balanced vesicle trafficking cycle that regulates proper assembly of epithelial junction in normal intestinal mucosa. Altering this cycle by either increasing endocytosis or inhibiting exocytosis of junctional proteins results in AJ and TJ disassembly.