Fig 8. High expression of VCAM-1, P-selectin or E-selectin in tissues of L. interrogans- infected mice.

(A) Expression of different adhesion molecules of mononuclear-macrophages and neutrophils in the lung, liver and kidney tissues from L. interrogans-infected C3H/HeJ mice, estimated by immunohistochemistry for the indicated infection times. The arrows indicate the expression of different adhesion molecules. (B) Expressed adhesion molecules in the tissues from L. interrogans-infected mice, estimated by analysis using Image-Pro Plus software. Statistical data from experiments such as shown in A. Bars show the means ± SD of three independent experiments. *: p<0.05 vs the normal animals.