Fig 4.

Effect of galic acid (GA) on C. albicans biofilm of 24 h (A) and 48h (B).Biofilms were exposed to 2 and 4 times the MIC (10 and 20 mg/mL) of GA for 5 min or to amphotericin B (AmB, 2 μg ml^-1). Four times the MIC of GA (20 mg/mL) was insoluble in water and GA/HPβCD spray-dried microparticles were tested. Control refers to negative control. Each point represents the mean of the data from three independent experiments (n = 45); bars represent the standard deviation (SD). Kruskal-Wallis test and Dunn's Multiple Comparison post hoc test were used to compare the treatment groups against the negative control.***, P ≤ 0.001; ns, not significant.