Table 2. Affinity constants of mAbs for epsilon toxin.
mAb | koff (s–1) | kon (M–1s–1) | KD (M) |
---|---|---|---|
PεTX2 | (1.0 ± 0.9) × 10−4 | (1.0 ± 0.1) × 104 | (9.6 ± 8.2) × 10−9 |
PεTX5 | (1.1 ± 0.1) × 10−3 | (1.2 ± 0.2) × 105 | (9.8 ± 2.8) × 10−9 |
PεTX6 | (1.2 ± 0.1) × 10−4 | (6.2 ± 0.9) × 104 | (1.9 ± 0.5) × 10−9 |
PεTX7 | (7.0 ± 0.9) × 10−4 | (2.0 ± 0.5) × 105 | (3.7 ± 0.5) × 10−9 |
PεTX9 | (1.3 ± 0.1) × 10−4 | (6.1 ± 0.5) × 104 | (2.1 ± 0.4) × 10−9 |