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. 2017 Jul 12;12(7):e0180642. doi: 10.1371/journal.pone.0180642

Fig 1. Experimental setup and fetal outcomes after LPS induced insult and synthetic PIF treatment.

Fig 1

(A) Experimental setup: We used 4 experimental groups (n = 18 pregnant animals each group). Control group received PBS (200ul/day from postnatal day 0 until day 15 (P0-15) and 200ul PBS on P7. Synthetic PIF group received synthetic PIF (1ug/g mouse/day) from P0-15 and PBS on P7. LPS group received PBS from P0-15 and LPS (0.1ug/g mouse) on P7. LPS+sPIF group received synthetic PIF and LPS (as above). Fetal outcomes are presented in (B) fetal loss, (C) placental weight, and (D) fetal weight, and (E) Ratio placental/fetal weight. *p<0.05, **p<0.01, and ***p<0.001. sPIF: synthetic PreImplantation Factor; LPS: Lipopolysaccharides. Data are mean ± SD.