Table 3.
Incidence of anemia and mortality during the 14-day amphotericin induction period among COAT participants with hemoglobin ≥8.5g/dL at diagnosis.
| Anemia Adverse Event (AE) Incidence | Status at 2 Weeks | ||
|---|---|---|---|
| Alive | Died | Overall | |
| Hemoglobin remained≥8.5g/dL | 33 (33.7%) | 7 (33.3%) | 40 (33.6%)a |
| Grade 2 AE, hemoglobin 7.5-8.4g/dL | 18 (18.4%) | 3 (14.3%) | 21 (17.7%) |
| Grade 3 AE, hemoglobin 6.5-7.4g/dL | 21 (21.4%) | 3 (14.3%) | 24 (20.2%) |
| Grade 4 AE, hemoglobin <6.5g/dL | 26 (26.5%) | 8 (38.1%) | 34 (28.6%) |
| Total | 98 | 21 | 119 |
a
One person died prior to receiving an additional hemoglobin measurement.