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. Author manuscript; available in PMC: 2018 Jun 28.
Published in final edited form as: Cancer Lett. 2017 Mar 14;396:145–154. doi: 10.1016/j.canlet.2017.03.011

Figure 5. Effect of regorafenib and paclitaxel on body weight, cardiac troponin I level, white blood cells and platelets in nude athymic mice.

Figure 5

(A) The changes in mean body weight of mice (n = 8) before and after the treatment. NS, not statistically significant (P > 0.05). (B) The changes in mean levels of cardiac troponin I in nude mice (n = 8) at the end of the 18-day treatment period. *P < 0.05 versus the vehicle group; #P < 0.05 versus the paclitaxel group; one-way ANOVA with Bonferroni post-test. (C) The changes in mean white blood cells in nude mice (n = 8) at the end of the 18-day treatment period. (D) The changes in mean platelets in nude mice (n = 8) at the end of the 18-day treatment period. *P < 0.05 versus the vehicle group; one-way ANOVA with Bonferroni post-test.