Table 1.

Characteristics of the synthesized HPMA copolymers

Copolymer	Mw (kDa)	PDI	Rh (nm)a	Tyrosine (Wt %)	Cy5 (Wt %)	Yield (%)
S-BP	17.4	1.03	2.85	−	−	87.6b
S-dBP	17.1	1.03	2.82	1.40	−	88.3c
S-MP	91.3	1.35	7.33	−	−	21.4d
S-CMP	92.5	1.34	7.21	−	0.31	91.7
L-BP	32.9	1.03	4.11	−	−	82.9 b
L-dBP	31.1	1.05	4.02	1.36	−	85.2c
L-MP	139.3	1.37	9.76	−	−	17.3d
L-CMP	140.5	1.39	9.85	−	0.37	93.5

^aHydrodynamic radius detected by Viscotek TDAmax system

^bYield of RAFT polymerization

^cYield of reduction and deprotection by hexylamine and TCEP.

^dYield of copolymer chain extension after fractionation