Table 1. Participant Characteristics.
Migraine and healthy control subjects had similar age, sex, and anxiety scores. Although migraine participants had statistically higher depression scores, the mean depression scores amongst the migraine patients and the healthy control patients were both within “normal” or non-depressed ranges. As expected, migraine participants had higher scores for hyperacusis, photophobia and allodynia. Anxiety scores were calculated from the State-Trait Anxiety Inventory. Allodynia scores during and between headaches were calculated from the Allodynia Symptom Checklist 12. Hyperacusis scores were calculated from the Hyperacusis Questionnaire. Photophobia scores were derived from the Photosensitivity Assessment Questionnaire. MIDAS = migraine disability assessment scale. SD = standard deviation.
| Migraine (n= 66) | Healthy Controls (n= 54) | p-value | |
|---|---|---|---|
|
Age in years (mean +/− SD) (n=120) |
36 +/− 11 | 36.5 +/− 11.2 | .82 |
|
Sex (female:male) (n=120) |
52:14 | 39:15 | .53 |
|
State Anxiety (mean +/− SD) (n=120) |
26.8 +/− 7.1 | 24.8 +/− 5.3 | .08 |
|
Trait Anxiety (mean +/− SD) (n=120) |
31.6 +/− 8.9 | 28.8 +/− 7.9 | .08 |
|
Beck Depression Inventory (mean +/− SD) (n=120) |
4.1 +/− 4.3 | 2.2 +/− 4 | .01* |
|
Hyperacusis (mean +/− SD) (n=114; data not available from 6 migraineurs) |
8.6 +/− 1.4 | 3.9 +/− 3.5 | <.001* |
|
Photophobia (mean +/− SD) (n=114; data not available from 6 migraineurs) |
2.4 +/− 2.5 | 1.0 +/− 1.7 | <.001* |
|
Allodynia Between/Without Headaches
(mean +/− SD) (n=120) |
0.8 +/− 0.4 | 0.1 +/− 0.4 | .01* |
|
Headache Days/ Month (mean +/− SD) (n=66) |
8.9 +/− 6.2 | ||
|
Years with Migraine (mean +/− SD) (n=66) |
16.2 +/− 10.4 | ||
|
Migraine Aura (yes/no) (n=60) |
26/34 | ||
|
MIDAS (mean +/− SD) (n=66) |
20.5 +/− 19 | ||
|
Allodynia During Headache (mean +/− SD) (n=66) |
4.9 +/− 1.6 |