Table 5. Comparison of Migraine Subjects in Sub-Group #1 vs. Sub-Group #2.

Migraine subjects in sub-group #1 had a greater number of years with migraine, more migraine-related disability, and greater symptoms of allodynia during migraine attacks. Allodynia scores during and between headaches were calculated from the Allodynia Symptom Checklist 12. Anxiety scores were calculated from the State-Trait Anxiety Inventory. Hyperacusis scores were calculated from the Hyperacusis Questionnaire. Photophobia scores were derived from the Photosensitivity Assessment Questionnaire. MIDAS = migraine disability assessment scale. SD = standard deviation.

	Migraine: Sub-Group #1 (n= 34)	Migraine: Sub- Group #2 (n= 32)	p-value
Age in years (mean +/− SD)  (n=66)	37.3 +/− 9.9	34.7 +/− 12	.35
Sex (female:male)   (n=66)	29:5	23:9	.23
Headache Days/ Month (mean +/− SD)   (n=66)	9.6 +/− 7.3	8.1 +/− 4.9	.32
Years with Migraine (mean +/− SD)   (n=66)	19.2 +/− 11.3	13 +/− 8.3	.01*
Migraine Aura (yes/no)   (n=60)	15/16	11/18	.45
MIDAS (mean +/− SD)   (n=66)	25 +/− 22.9	15.7 +/− 12.2	.04*
Allodynia During Headache (mean +/− SD)   (n=66)	6.1 +/− 5.3	3.6 +/− 3.2	.03*
Allodynia Between Headaches (mean +/− SD)   (n=66)	1 +/− 2.4	0.6 +/− 1.7	.36
Hyperacusis (mean +/− SD)   (n=60)	7.5 +/− 6	9.8 +/− 7.3	.17
Photophobia (mean +/− SD)   (n=60)	2.2 +/− 2.7	2.7 +/− 2.3	.39
State Anxiety (mean +/− SD)   (n=66)	27.3 +/− 7.8	26.3 +/− 6.3	.58
Trait Anxiety (mean +/− SD)   (n=66)	32.5 +/− 10.3	30.6 +/− 7.2	.39
Beck Depression Inventory (mean +/− SD)   (n=66)	4.7 +/− 4.6	3.6 +/− 4	.30