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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Eur J Nucl Med Mol Imaging. 2017 Apr 5;44(9):1501–1510. doi: 10.1007/s00259-017-3676-6

Table 1.

Summary of imaging findings and surgical plan in patients with lymphedema

Staging ICG PET-CT MRL Surgical Plan
Stage I Linear/Splash Less visualized lymphatic vessels; delay of probe transport on PET; no obvious DB appearance of the subcutis; lymph node accumulation defect on the affected side Less visualized lymphatic vessels; delay of contrast agent transport LVA
Stage II Stardust “Honeycomb Pattern”; probe accumulation between fat surrounded by fibrotic tissue; lymph node accumulation defect on the affected side “Honeycomb Pattern”; contrast agent accumulation between fat surrounded by fibrotic tissue LVA + SAPL
Stage III Diffuse Large, irregular, patchy shaped DB; locally increased tracer uptake; dilated lymph vessels and damaged lymph vessels even with severe fibrosis; tortuous and deep-seated lymph vessels; lymph node accumulation defect on the affected side Large, irregular, patchy shaped DB; increased subcutaneous thickness and diffuse fibrosis; dilated lymph vessels and damaged lymph vessels even with severe fibrosis; tortuous and deep-seated lymph vessels SAPL

DB, dermal backflow; LVA, lymphaticovenous anastomosis; SAPL, suction-assisted protein lipectomy