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Common drug-related adverse events (≥ 10%) observed in N1087 trial.
| Grade 1–2 | Grade 3–4 | |||
|---|---|---|---|---|
| hematological toxicity | N | % | N | % |
| Neutropenia | 3 | 23.1 | 6 | 46.2 |
| Platelet count decrease | 6 | 46.2 | 2 | 15.4 |
| Anemia | 7 | 53.8 | ||
| Febrile neutropenia | 3 | 23.1 | ||
|
| ||||
| Grade 1–2 | Grade 3–4 | |||
|
| ||||
| non-hematological toxicity | N | % | N | % |
| Nausea | 6 | 46.2 | 1 | 7.7 |
| Diarrhea | 3 | 23.1 | 2 | 15.4 |
| Rash | 3 | 23.1 | 2 | 15.4 |
| Vomiting | 3 | 23.1 | 1 | 7.7 |
| Hyperglycemia | 4 | 30.8 | ||
| Mucositis | 3 | 23.1 | ||
| Fever | 2 | 15.4 | ||
| Fatigue | 2 | 15.4 | ||
| Sinus Bradycardia | 2 | 15.4 | ||
