Fig. 2.

Determination of effects of SB203580 and SB202190 on cell proliferation. a MDA-MB231 cells (12,500) were seeded in each well of E-plate L8 and treated with 1 µM SB203580, 5 µM SB203580, 50 µM SB203580, 1 µM SB202190, 5 µM SB202190 or 50 µM SB202190 for approximately 96 h. The cell index (CI) was monitored every hour by using the iCELLigence system. The results are mean ± standard deviation (n = 2 or 3), b proliferation values of MDA-MB-231 cells at the 42 h of inhibitor treatments. The results are presented as the mean ± SEM (n = 2 or 3), c effect of 10 nM, 100 nM and 500 nM of SB203580 and SB202190 on MDA-MB-231 cell proliferation, d graphical representation of the effect of low doses of SB203580 and SB202190 at the 42 h of inhibitor treatments. The results are presented as the mean ± SEM (n = 2 or 4). The error bars are not visible in some bars on account of small variations