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. 2017 Jul 12;7:5245. doi: 10.1038/s41598-017-05340-x

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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DCX C-terminal deletion slows dynamic association with MTs and decreases sensitivity to taxol-induced MT changes. (A–C) The recovery of the ROI fluorescence for GFP-DCX WT and GFP-DCX ΔC under basal, nocodazole or taxol treatments. Results are for the mean ± SEM for (A) the initial rate of recovery of fluorescence for GFP-DCX WT or GFP-DCX ΔC in the photobleached area (estimated over the initial 6 s post-bleach), (B) the time to reach half-maximal recovery of fluorescence (t_1/2), and (C) the fluorescence maximum recovery for GFP-DCX WT or GFP-DCX ΔC in the bleached area. Error bars represent the standard error of the means and asterisks indicate values calculated to be statistically significantly different (*p ≤ 0.05, **p ≤ 0.01, ****p ≤ 0.0001 n = 10 cells in each of three independent experiments. n.s. = not significant).