Fig. 5.

Changes in the one-repetition maximum as an estimate of leg muscle strength in the creatine and placebo group, following 7 days of one-legged knee immobilization and 7 days of subsequent recovery. Data were analyzed by two-way repeated measures ANOVA with time as a within-subjects factor and treatment (creatine and placebo group) as between-subjects factors. Data are expressed as means ± standard error of the mean. Immobilization resulted in a significant decline in muscle strength in both groups (asterisk), with no differences between groups. Muscle strength did not change during the recovery week, with no differences between groups. 1-RM one-repetition maximum