Figure 4.

Body weight (A) in RA (white bars) and O₂-exposed (100% O₂ for 10 days; shaded bars) rat pups injected with 0.9% NaCl or BMP9 (2.5 μg kg⁻¹ twice daily for 10 days). Data are expressed as mean ± SEM. Differences between groups were analyzed by one-way ANOVA, followed by Tukey's multiple comparisons test. ^***p < 0.001 vs. age-matched 0.9% NaCl treated RA controls. Kaplan-Meier survival curves (B) of BMP9-treated rat pups exposed to 100% O₂ (Δ), age-matched O₂-exposed controls (•) and room air exposed controls treated with BMP9 (□) or 0.9% NaCl (▾) for 10 days after birth. Data are expressed as mean percentage ± SEM of pups surviving at the observed time point. N = 18–24. ^*p < 0.05 vs. age-matched 0.9% NaCl treated RA controls.