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. 2017 Jul 13;8:499. doi: 10.3389/fphys.2017.00499

Table 2.

Curve parameters (a, b, and c) describing the relationships between V˙E and V˙CO2, between HR and V˙O2 and between VT and V˙E.

EP-born participants Term-born participants
Male (n = 11) Female (n = 20) Male (n = 12) Female (n = 22)
1991–1992 birth-cohort (age 10 years)
V˙E = a + b·V˙CO2
a 2.4 ± 1.5 2.2 ± 1.4 2.3 ± 1.3 2.1 ± 1.6
b 32.8 ± 2.1* 32.1 ± 2.8 29.5 ± 2.2 30.7 ± 3.4
HR = a + b·V˙O2
a 75 ± 12 70 ± 10 74 ± 13 77 ± 16
b 93 ± 10* 100 ± 15* 79 ± 9 82 ± 18
VT = a + b·V˙E + c·V˙E2
a 0.17 ± 0.09 0.17 ± 0.10 0.14 ± 0.10 0.22 ± 0.20
b (·10−2) 2.4 ± 1.0 2.6 ± 0.6 3.0 ± 0.9 2.8 ± 0.8
c (·10−4) −2.0 ± 1.6 −1.9 ± 1.0 −2.1 ± 1.1 −2.1 ± 1.4
Male (n = 20) Female (n = 17) Male (n = 25) Female (n = 20)
1982–1985 birth-cohort (age 18 years)
V˙E = a + b·V˙CO2
a 2.7 ± 1.7 3.3 ± 1.9 2.3 ± 2.0 4.2 ± 1.6
b 25.4 ± 2.0 26.2 ± 3.9 25.1 ± 2.8 25.2 ± 3.1
HR = a + b·V˙O2
a 65 ± 11 68 ± 13 68 ± 12 75 ± 14
b 40 ± 8 57 ± 9 39 ± 5 51 ± 12
VT = a + b·V˙E + c·V˙E2
a 0.24 ± 0.20 0.09 ± 0.17 0.29 ± 0.16 0.17 ± 0.16
b (·10−2) 3.7 ± 0.9 4.5 ± 1.2 3.8 ± 0.9 4.0 ± 1.1
c (·10−4) −1.8 ± 0.8 −3.5 ± 1.9* −1.7 ± 1.0 −2.4 ± 1.1

Mean ± 1 standard deviation.

*

significantly different from controls of same sex p < 0.05

V˙O2 oxygen uptake, V˙CO2 carbon dioxide output, V˙E minute ventilation, HR heart rate.