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. 2017 Jul 12;7:5178. doi: 10.1038/s41598-017-05461-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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ROS generation in SNPs ■ and ASNPs □ treated MDA-MB-231 cells. Ctrl+ represents positive control cells, which are treated by H₂O₂. Relative fluorescence of DCF was measured using a spectrofluorometer with excitation at 485 nm and emission at 530 nm. Each column represents the mean value of three measurements. The error bars were calculated by dividing the standard deviation by the square root of the number of measurements.