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. Author manuscript; available in PMC: 2017 Jul 13.
Published in final edited form as: Methods Mol Biol. 2017;1486:357–390. doi: 10.1007/978-1-4939-6421-5_14

Fig. 5.

Fig. 5

Stage-wise unfolding and refolding a single gp41 SNARE complex (36). (A) Force-extension curves (FECs) obtained by pulling (black) and relaxing (cyan) the gp41 complex. The continuous regions of the FECs are fit with a worm-like chain model (red lines), revealing different gp41 folding states (6HB, 5HB, and the fully unfolded state). (B) Time-dependent extension, force, and trap separation corresponding to the force and extension shown in A. A close-up view of the region marked by the dashed box is shown as an inset.