Fig. 6.
Two-state gp41 hairpin folding and unfolding transition. (A) Extension-time trajectories (black) at three constant mean forces (F) or trap separations (D). The red lines are the idealized extension trajectory derived from hidden-Markov modeling. (B) Probability density distributions of the extensions shown in A. (C) Probability density distributions of the extension at 8.3 pN calculated after mean-filtering the trajectory using three time windows (0.2, 2, and 50 ms).