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. 2017 Jul 12;37(28):6751–6760. doi: 10.1523/JNEUROSCI.0291-17.2017

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Copyright © 2017 Auksztulewicz et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 3. — A, Source reconstruction. Sources of strongest activity evoked by the onset of the auditory sequences were localized to bilateral putative auditory and inferior frontal cortices. B, Source-level time-frequency contrasts. Each panel shows t statistics as time-frequency maps (large panels; highlighted cluster exceeds corrected significance threshold at FWE = 0.05) and time-averaged frequency spectra (small panels; red lines: thresholds of significance at FWE = 0.05). Gray bars indicate notch filter and harmonic. Bar plot inset shows post hoc t tests and 95% confidence intervals for the significant time-frequency cluster showing an interaction of regularity and alphabet size on induced power in auditory cortex (82 Hz, 1500 ms), dominated by the difference in high-frequency power between REG5 and RAND5 conditions. Source activity inset shows that the high-frequency interaction effect at 1500 ms can be specifically assigned to early auditory regions in a whole-brain analysis. Asterisks mark significance after FWE correction.